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Ionis Cuts 2026 Tryngolza Sales Outlook to About $50 Million

The prior target was $100 million to $110 million, while third-quarter revenue reached $243 million.

Updated 1 min read
Employees enter a biotechnology campus on a cloudy morning in Carlsbad, California. (AI-generated image / EconoTimes)
Employees enter a biotechnology campus on a cloudy morning in Carlsbad, California. (AI-generated image / EconoTimes)

Ionis Pharmaceuticals lowered its 2026 Tryngolza sales outlook to about $50 million, while companywide results for the third quarter exceeded expectations for revenue and earnings.

The company set a 2026 sales target of about $50 million for Tryngolza. Its earlier outlook ranged from $100 million to $110 million.

Tryngolza is used to treat severe hypertriglyceridemia. For the quarter ended Sept. 30, Ionis reported $243 million in revenue and a GAAP loss of $0.66 per share.

Those revenue and loss figures cover Ionis overall for the quarter; the $50 million outlook applies to Tryngolza sales for the full year.

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