Bloomberg reported Novartis will end development of pelacarsen for atherosclerotic cardiovascular disease after its September 2026 trial failure, while continuing one calcific aortic valve stenosis study.

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Ionis Pharmaceuticals discovered pelacarsen. Novartis said its Phase 3 Lp(a)HORIZON trial missed its primary endpoint in September 2026.

Bloomberg reported Novartis will end development of pelacarsen for atherosclerotic cardiovascular disease after its September 2026 trial failure, while continuing one calcific aortic valve stenosis study.
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