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Thomas Durcan

Assistant Professor, Neurodegenerative disorders, McGill University
As an assistant professor at the Montreal Neurological Institute (MNI) and McGill University, my research focus is on applying patient-derived stem cells towards the development of phenotypic discovery assays and 3D mini-brain models for both neurodegenerative and neurodevelopmental disorders. As group leader of the iPSC platform at the Montreal Neurological Institute (MNI), I oversee a team of 30 research staff and students and growing, committed to applying novel stem cell technology, combined with CRISPR genome editing, mini-brain models and new microfluidic technologies towards elucidating the underlying causes of these complex disorders. Leading the SGC tissue platform, NeuroSGC; I oversee a team committed to assay development, in parallel with leading the establishment of NeuroCDRD, towards the automation of our open assays for small molecule screens. In addition, I am also part of antibody validation efforts between the MNI, Oxford and the Karolinska to generate CRISPR KO cell-lines for validating commercial antibodies against high-value ALS targets. Combined with new approaches in the group towards building multiomic profiles on the patient-derived IPSC cells within the group, the long-term strategy over the coming years is to identify new personalized precision therapies that can be applied towards building clinical trials on a dish.

To cure brain diseases, neuroscientists must collaborate: That's why I'm giving my data away

Jul 07, 2019 15:11 pm UTC| Insights & Views Technology

Since watching Jurassic Park for the first time as a kid, Ive been fascinated by the biology of cells and DNA, and the potential to make a dinosaur for real. While this particular dream is a long way off, my life as a...

Economy

Gold Price Surges Above $4,100 as Middle East Tensions Boost Safe-Haven Demand

Gold prices extended their rally on Wednesday, climbing above the key $4,100-an-ounce level as investors sought safe-haven assets amid escalating Middle East tensions and growing concerns over global energy supplies....

US Stock Exchanges Face Earnings Test as Trading Boom Meets Crypto Competition

U.S. exchange operators are set to begin reporting quarterly earnings this week, with investors expected to focus on whether strong trading activity can offset mounting concerns over regulatory changes and rising...

India FMCG Q1 Earnings Preview: Higher Input Costs Likely to Weigh on Profit Margins

Indias leading fast-moving consumer goods (FMCG) companies are expected to report weaker first-quarter profit margins as rising raw material costs, driven by the Iran conflict and higher crude oil prices, offset the...

Saudi Oil Tankers Reverse Course as Houthi Threats Disrupt Red Sea Shipping

Two oil tankers carrying Saudi crude to Asia reversed course in the Red Sea after Yemens Iran-backed Houthi movement threatened to target vessels transporting Saudi oil, raising fresh concerns over global energy supplies...

Pakistan Seeks $10 Billion U.S. Exchange Stabilization Fund to Boost Forex Reserves

Pakistan has asked the United States for a $10 billion exchange stabilization facility to strengthen its foreign exchange reserves and reduce pressure on the Pakistani rupee, according to a Reuters report citing a source...

Politics

US-Backed Pediatric HIV Treatment Drops After Foreign Aid Changes, Study Finds

Around 77,000 fewer children worldwide received HIV treatment supported by the United States in the fiscal year ending October 2025 compared with the previous year, according to research presented at the AIDS 2026...

US, Solomon Islands Deepen Ties as Peace Corps Set to Return After 25 Years

The United States is strengthening its relationship with the Solomon Islands by reviving the Peace Corps program and expanding development assistance, signaling Washingtons continued focus on the strategically important...

US Sends First Humanitarian Aid Flight to Cuba Under $100M Assistance Plan

The United States has launched the first humanitarian aid flight to Cuba under a newly announced $100 million assistance initiative, marking a significant step in Washingtons effort to provide direct relief to the Cuban...

Rubio to Meet Wang Yi as Trump-Xi Summit Plans Advance Amid Election Meddling Dispute

U.S. Secretary of State Marco Rubio is set to meet Chinese Foreign Minister Wang Yi in Manila this week, a key diplomatic engagement that could pave the way for a highly anticipated summit between U.S. President Donald...

US Military Completes 11th Straight Day of Iran Strikes Amid Strait of Hormuz Security Concerns

The U.S. military has completed its 11th consecutive day of airstrikes against Iran, intensifying efforts to weaken Tehrans military capabilities and protect one of the worlds most strategically important shipping routes....

Science

Blue Origin New Glenn Explosion Could Delay Launch Operations Until 2028

Blue Origin is facing a significant setback after a dramatic explosion involving its New Glenn rocket severely damaged a launch pad at Cape Canaveral, Florida. According to NASA Administrator Jared Isaacman, repairs to the...

Blue Origin New Glenn Rocket Explodes During Launch Pad Test, Delaying Space Ambitions

Blue Origin suffered a major setback after its uncrewed New Glenn rocket exploded during a launch pad test in Florida on Thursday, raising new challenges for Jeff Bezos space company as it competes with Elon Musks SpaceX...

SpaceX Delays Starship V3 Launch Ahead of Potential Record IPO

SpaceX on Thursday postponed the highly anticipated launch of its 12th Starship rocket test from Texas after technical issues interrupted the final countdown. The company now plans to attempt the Starship V3 launch again...

Trump Administration Releases New UFO Files and Apollo Mission Records

The U.S. Defense Department has released dozens of previously classified UFO-related files following an order from President Donald Trump, sparking renewed debate over unidentified anomalous phenomena (UAP) and government...

China vs. NASA: The New Moon Race and What's at Stake by 2030

The space race is back and this time, its a direct competition between the United States and China for dominance on the lunar surface. NASAs Artemis II mission recently made history when four astronauts flew farther into...

Technology

Wistron Opens $700M Texas AI Factory to Build Nvidia Superchips in U.S.

Taiwan-based Wistron Corp. (TW:3231), one of Nvidias leading manufacturing partners, has officially opened its first U.S. production facility in Fort Worth, Texas, marking a significant milestone in the expansion of...

Wistron Opens $700M Texas AI Factory to Build Nvidia GB300 Superchips

Taiwan-based Wistron Corp., a major Nvidia supplier, has opened its first U.S. manufacturing facility in Fort Worth, Texas, investing $700 million to expand artificial intelligence infrastructure production as global...

Super Micro Computer Stock Jumps 20% After Record AI Orders and Margin Surge

Super Micro Computer (NASDAQ: SMCI) stock soared about 20% in after-hours trading on Tuesday after the AI server maker released a stronger-than-expected preliminary update for its fiscal fourth quarter, highlighting a...

US, China to Hold AI Talks Ahead of Xi’s September Visit

The United States and China are preparing to hold high-level artificial intelligence (AI) talks in September, marking the first official AI dialogue between the two countries under President Donald Trumps administration....

Morgan Stanley Downgrades Adobe, Workday as AI Transition Raises Growth Concerns

Morgan Stanley adopted a mixed outlook on the software sector on Tuesday, turning bearish on Adobe (NASDAQ: ADBE) and Workday (NASDAQ: WDAY) while maintaining an overall positive view of the industry. The investment bank...