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Merlin Crossley

Deputy Vice-Chancellor Academic and Professor of Molecular Biology, UNSW

I have been doing molecular biology since 1985 and been in academic administration since 2004. I continue to run a large laboratory and to teach at UNSW Sydney.

My lab has a blog with posts every Friday https://wordpress.com/view/crossleylab.wordpress.com

our lab website is http://www.crossleylab.unsw.edu.au/

We work on DNA-binding proteins that facilitate epigenetic changes to turn genes on and off. We are interested in developing ways to artificially regulate the expression of particular genes. For instance, recently we have used CRISPR and other gene editing approaches to introduce beneficial mutations to boost the output of medically important genes. Such technologies may be useful in treating particular genetic diseases of the blood, like sickle cell anemia, and of metabolism, such as diabetes and obesity.

I enjoy teaching and give lectures in the area of molecular biology, genomics, epigenetics, stem cells, genetic reprogramming and genome editing.

I have written extensively on modern molecular genetics and on science teaching and education policy.

New CRISPR technology could revolutionise gene therapy, offering new hope to people with genetic diseases

Feb 02, 2021 13:12 pm UTC| Science

The day a muddled mob stormed the US Capitol building, a team of American researchers published a paper in Nature that signified a landmark in gene therapy. The head of the US National Institutes of Health, Francis...

Boyer Lectures: gene therapy is still in its infancy but the future looks promising

Oct 16, 2018 15:12 pm UTC| Insights & Views Science

This year marks the 60th anniversary of the ABCs Boyer Lectures. Delivered by Professor John Rasko, the 2018 Life Engineered lectures explore ethical and other issues around gene therapy and related technologies, and their...

When to trust (and not to trust) peer reviewed science

Jul 14, 2018 11:10 am UTC| Insights & Views Science

The article is part of our occasional long read series Zoom Out, where authors explore key ideas in science and technology in the broader context of society. The words published in a peer reviewed journal are sometimes...

Economy

New World Screwworm Found Near U.S. Border Raises Threat to Cattle Industry and Beef Prices

A dangerous outbreak of the New World Screwworm has moved closer to the United States, raising serious concerns for the livestock industry and agricultural economy. According to the U.S. Department of Agriculture (USDA),...

Iran-U.S. Nuclear Talks Remain Unresolved as Strait of Hormuz Risks Keep Markets on Edge

Iran has rejected suggestions that a final agreement has been reached with the United States, emphasizing that negotiations surrounding its nuclear program remain ongoing. The statement came after comments from U.S....

US Launches New Trade Investigation Into Vietnam Over Intellectual Property Concerns

The United States has initiated a new trade investigation into Vietnams handling of intellectual property (IP) rights, a move that could eventually lead to additional tariffs on Vietnamese imports. The investigation,...

US Dollar Slips as Markets Weigh Potential US-Iran Peace Deal and Oil Price Outlook

The U.S. dollar weakened slightly on Friday as investor confidence improved following comments from President Donald Trump regarding a possible peace agreement between the United States and Iran. The prospect of easing...

Oil Prices Fall as Markets Await U.S.-Iran Peace Deal Decision

Oil prices moved lower on Friday as investors closely monitored developments surrounding a potential U.S.-Iran peace agreement. Market sentiment weakened after U.S. President Donald Trump stated that he would meet with...

Politics

US Southern Command Chief Holds Rare Military Meeting With Cuban Officials at Guantanamo Bay

A rare high-level military meeting between the United States and Cuba took place at the perimeter of the U.S. Naval Station at Guantanamo Bay, marking a significant development in U.S.-Cuba relations amid growing...

Trump Nears Decision on Iran Ceasefire Extension as Key Disputes Remain

U.S. President Donald Trump said Friday that he is close to making a final decision on a proposed agreement to extend the current ceasefire with Iran, although major disagreements between Washington and Tehran continue to...

Poland Considers Revoking Zelensky’s Top Honor Over Controversial UPA Army Unit Recognition

Poland is considering revoking one of its highest state honors awarded to Ukrainian President Volodymyr Zelensky after a controversial decision by Ukraine to rename a military unit after the Ukrainian Insurgent Army (UPA),...

Trump Signs Executive Order to Expand Access to Federal Lands in the U.S.

U.S. President Donald Trump signed an executive order on Friday aimed at removing restrictions that limit access to federal lands across the United States, according to a statement from the White House. The move is part of...

UN Blacklists Israel and Russia Over Conflict-Related Sexual Violence Claims

The United Nations has added Israel and Russia to its official blacklist of parties suspected of committing conflict-related sexual violence, a decision that has sparked strong international reactions and intensified...

Science

Blue Origin New Glenn Rocket Explodes During Launch Pad Test, Delaying Space Ambitions

Blue Origin suffered a major setback after its uncrewed New Glenn rocket exploded during a launch pad test in Florida on Thursday, raising new challenges for Jeff Bezos space company as it competes with Elon Musks SpaceX...

Trump Administration Releases New UFO Files and Apollo Mission Records

The U.S. Defense Department has released dozens of previously classified UFO-related files following an order from President Donald Trump, sparking renewed debate over unidentified anomalous phenomena (UAP) and government...

China vs. NASA: The New Moon Race and What's at Stake by 2030

The space race is back and this time, its a direct competition between the United States and China for dominance on the lunar surface. NASAs Artemis II mission recently made history when four astronauts flew farther into...

NASA Artemis II: First Crewed Moon Mission Since Apollo Takes Four Astronauts on 10-Day Lunar Journey

NASAs Artemis II mission launched Wednesday, marking humanitys return to crewed lunar exploration for the first time since the Apollo era. Carrying four astronauts aboard the Orion spacecraft, this historic 10-day mission...

NASA's Artemis II Mission: First Crewed Lunar Journey Since Apollo

Technology

Kentucky School District Secures $27 Million in Social Media Addiction Lawsuit Settlements

A Kentucky school district has secured nearly $27 million in settlements from major social media companies over allegations that their platforms contributed to a growing student mental health crisis. The financial details,...

MongoDB Q1 FY2027 Earnings Beat Expectations, Raises Full-Year Outlook

MongoDB (NASDAQ: MDB) delivered stronger-than-expected first-quarter fiscal 2027 results, fueled by growing demand for its database platform among enterprises and organizations developing artificial intelligence...

SpaceX IPO Could Become Largest in History with $1.8 Trillion Valuation Target

Elon Musks SpaceX is reportedly moving forward with plans for a historic initial public offering (IPO), targeting a valuation of at least $1.8 trillion. According to a Bloomberg News report citing sources familiar with the...

Autodesk Beats Q1 Estimates, Acquires MaintainX for $3.6 Billion

Autodesk (NASDAQ: ADSK) reported stronger-than-expected financial results for its fiscal first quarter and announced a major $3.6 billion acquisition of MaintainX, a move that strengthens its position in AI-powered...

US Quantum Stocks Surge After $2 Billion Government Investment

The U.S. Department of Commerce has sparked major excitement across the technology and financial sectors after announcing plans to invest $2 billion into quantum computing and advanced hardware companies through the CHIPS...