Global Viral Vector Development Service: Market Overview and Future Opportunities By Profshare Market Research

Tuesday, February 27, 2018 9:12 AM UTC

NEW YORK, Feb. 27, 2018 -- Viral vector is gene transfer therapy use to manipulate and modify specific cell type or tissue. It is most effective gene manipulation technique used globally. Various virus types are use in viral vector process to provide either transient or permanent gene delivery to cells. Viral vector process based on virus included are:

Retroviral Vectors – Retroviruses are stably integrate their genomes into host cell chromosomes. These viruses are positive strand RNA viruses and can enter virtually any mammalian cell type. Retroviruses can carry foreign genes of around 8 kb.
Lentiviral Vectors – Lentiviruses are a subgroup of the retrovirus family and allow stable, long-term expression into the host cell genome.
Adenoviral Vectors – Adenoviruses are DNA viruses can transiently transduce nearly any mammalian cell type. The adenovirus enters target cells by binding to the Coxsackie/Adenovirus receptor (CAR). The packaging capacity of adenoviruses is 7–8 kb.
Adeno-associated Viral Vectors – Adeno-associated viruses are capable of transducing a broad range of dividing and non-dividing cells types, with a helper virus like adenovirus or herpes virus to produce recombinant visions in packaging cells. Adeno-associated viruses have packaging capacity of up to 4.9 kb.
Other Viral Vectors – Other viral vector systems based on vaccinia virus, herpes simplex virus, baculovirus.

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Viral Vectors technique relies completely on viruses. The choice of virus for Viral Vectors process depend on

Safety: Pathogenic viruses are used occasionally to create viral vectors, they are modified in specific way to minimize handling risk.
Low toxicity: The viral vector should have as minimal as possible effect on tissue or cell it infects. It has vital importance in studies requiring gene delivery in vivo as immune response will get developed in organism against foreign cell body.
Stability: Some viruses are genetically unstable and can rapidly rearrange their genomes. Hence unstable vectors are usually avoided in Viral Vectors process.
Cell type specificity: Most viral vectors are constructed to infect as wide a range of cell types as possible and sometimes the opposite is preferred.
Selection: Viral vectors should contain selectable properties like resistance to a certain antibiotic, so that the cells that have taken up the viral vector can be isolated.

Viral Vector Development Service Market: End User/Application

Pharmaceutical Manufacturers
Biotechnology Companies
Research Institutes

Viral Vector Development Service Market: Product Type

Retroviral Vectors
Lentiviral Vectors
Adenoviral Vectors
Adeno-associated Viral Vectors
Other Viral Vectors

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Viral Vector Development Service Market: Competition Analysis

This reports covers in depth analysis of major players of Viral Vector Development Service Market. Competition Analysis included in study covers Company Profile, Products, Services and Solutions, Viral Vector Development Service Revenue (Value), Recent Developments. Some of key players in market are: