The Korea Institute of Energy Research (KIER) had developed an enzymatic process that uses agricultural waste to produce the 4-hydroxy valeric acid--an ingredient for biofuels and plastics.
The KIER's enzymatic process would hydrogenate levulinic acid, which in turn is created by subjecting non-edible agricultural waste biomass, such as rice straw and cornstalk, to an oxidation process.
In the natural world, there is no enzyme that can hydrogenate levulinic acid.
But researchers at KIER were able to modify the ternary molecule structure of an enzyme that can hydrogenate acetoacetic acid with a similar structure to levulinic acid.
That modified enzyme was then designed to be able to hydrogenate levulinic acid.
A byproduct of levulinic acid is formic acid which generates the hydrogen needed for the reaction.


Trump Administration to Launch Autism Initiatives Targeting Acetaminophen Use and New Treatment Options
Blue Origin New Glenn Rocket Explodes During Launch Pad Test, Delaying Space Ambitions
Neuralink Expands Brain Implant Trials with 12 Global Patients
Gold Prices Tumble 3% After Hawkish Fed Speech Boosts Dollar
France Inflation Accelerates to 2.7% in August
Jared Isaacman Confirmed as NASA Administrator, Becomes 15th Leader of U.S. Space Agency
Asian Stocks Mixed as KOSPI Falls Ahead of Fed Speech
Japan Firms Ramp Up Yen Hedging as Currency Weakness Persists
SpaceX Pivots Toward Moon City as Musk Reframes Long-Term Space Vision
US Dollar Hits Two-Week High After Hawkish Fed Speech
Asian Currencies Mixed as Dollar Holds Firm Ahead of Jackson Hole
Oil Prices Slip on Venezuela Supply, Iran Tensions
Trump Administration Releases New UFO Files and Apollo Mission Records
BOJ’s Himino Signals Timely Rate Hikes as Inflation Risks Rise
Asian Currencies Steady Ahead of Warsh Speech
Canadian Dollar Slides as Fed Rate Hike Bets Boost US Dollar 



