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Nial Wheate

Senior Lecturer in Pharmaceutics, University of Sydney

Dr Wheate completed a Bachelor of Science degree with 1st class honours from the University of New South Wales whilst at the Australian Defence Force Academy. He then completed a PhD in medicinal chemistry under Professor J. Grant Collins. Since then he has worked in the School of Biomedical and Health Sciences at the University of Western Sydney (Australia) and the Strathclyde Institute of Pharmacy and Biomedical Science (Scotland) before taking up a position in the Faculty of Pharmacy at the University of Sydney (Australia) in 2012.

Dr Wheate's research interests lie in whole-of-pipeline discovery and development of platinum-based anticancer drugs including: design and synthesis, in vitro and in vivo screening, drug-DNA binding, nanoparticle based delivery, solid state chemistry and co-crystals, toxicology and pharmacokinetics, and dosage formulation. Additionally, his research also examines the drug delivery application of macrocycles (including cyclodextrins, cucurbiturils and pillararenes) and their host-guest complexes.

Dr Wheate was previously the Head of Cancer Research in the Faculty of Pharmacy.

Weekly Dose: methylprednisolone, a drug for treating inflammation but not rare kidney disease

Aug 03, 2017 16:37 pm UTC| Health

Methylprednisolone is a prescription drug used to treat conditions involving inflammation, like asthma, arthritis, gout, tendinitis, transplant rejection, allergic reactions, and the skin conditions eczema and...

Explainer: what is chemotherapy and how does it work?

Jun 01, 2017 14:12 pm UTC| Health

Chemotherapy is the use of drugs to treat cancer in humans and animals. It is rarely used in isolation and is often paired with surgery, radiotherapy and immunotherapy, or a combination of these. Chemotherapy works by...

New drugs on the PBS: what they do and why we need them

May 05, 2017 02:05 am UTC| Insights & Views Health

This week, the government announced the latest additions, amendments, and deletions from the Pharmaceutical Benefits Scheme (PBS): the program through which essential medicines are subsidised for Australian patients. The...

Fentanyl, the anaesthetic that may have been used as a chemical weapon on Chechen rebels

Jul 27, 2016 07:35 am UTC| Health

Fentanyl is a synthetic analgesic (pain relieving) drug in the same class as morphine. It is used to treat acute or chronic pain, including for epidurals given to women during childbirth. It is thought that in 2002...

Economy

Impact of Iran-Israel conflict on Stocks, Gold and Bitcoin

Disclaimer: This is not investment advice. The information provided is for general purposes only. No information, materials, services and other content provided on this page constitute a solicitation, recommendation,...

Japan Posts 7.7% Growth in Machinery Orders

In a striking development that looks set to invigorate Japans economic prospects, a key gauge of capital spending in the country has seen its most significant jump in over a year. According to Cabinet Office data released...

How cuts to marginal income tax could boost the UK’s stagnant economic growth

The British prime minister recently claimed the UK economy has turned a corner. Rishi Sunak said inflation figures were encouraging, and proclaimed that 2024 would be the year Britain bounces back. According to his...

A sustainable future begins at ground level

In 2015, the United Nations adopted the Sustainable Development Goals (SDGs) as a call to action in global partnership. By 2023 it appears that our progress has been far from satisfactory in achieving these...

Digital trade protocol for Africa: why it matters, what’s in it and what’s still missing

In February 2024, African heads of states adopted a draft protocol to regulate digital trade within the continent. This significant yet challenging course for Africas digital economy fits into the broader trade agreement,...

Politics

Nvidia RTX 4090D Embroiled in US-China Tech Rivalry; South Korea Navigates Chip Export Dilemma

The U.S. government has tightened export restrictions on high-performance semiconductor chips to China, including the Nvidia RTX 4090D, and is urging South Korea to enforce similar curbs, marking a significant escalation...

Canada needs a national strategy for homeless refugee claimants

One year after the federal government closed Roxham Road, refugee claims in Canada continue to increase: there were 143,785 in 2023 compared to 91,730 in 2022. The surprise announcement in March 2023 to modify Canadas...

Who will Trump pick as his running mate?

Being second in line for leadership of the most powerful country in the world is not an easy job. But for Mike Pence, vice president under Donald Trump, things were even harder than usual. As insurrectionists descended...

US and Japan Boost AI, Semiconductor Alliance; EU Eyes Reduction in China Dependence

Japan and the United States are poised to deepen ties in the high-tech sector, signaling a strategic move to enhance their global partnership with a focus on artificial intelligence and semiconductor...

US Finalizes Ban List for Chinese Chipmakers; Boosts Mexico Semiconductor Ties

The United States is finalizing a list of Chinese chip factories banned from receiving vital technology, aiming to curb Beijings tech advancements amid national security concerns. Concurrently, a US-Mexico semiconductor...

Science

If life exists on Jupiter’s moon Europa, scientists might soon be able to detect it

Europa is one of the largest of more than 90 moons in orbit around the planet Jupiter. It is also one of the best places to look for alien life. Often termed an ocean world by scientists, observations to date strongly...

Exploding stars are rare but emit torrents of radiation − if one happened close enough to Earth, it could threaten life on the planet

Stars like the Sun are remarkably constant. They vary in brightness by only 0.1% over years and decades, thanks to the fusion of hydrogen into helium that powers them. This process will keep the Sun shining steadily for...

An eclipse for everyone – how visually impaired students can ‘get a feel for’ eclipses

Many people in the U.S. will have an opportunity to witness nearly four minutes of a total solar eclipse on Monday, April 8, 2024, as it moves from southern Texas to Maine. But in the U.S., over 7 million people are blind...

How do airplanes fly? An aerospace engineer explains the physics of flight

Airplane flight is one of the most significant technological achievements of the 20th century. The invention of the airplane allows people to travel from one side of the planet to the other in less than a day, compared...

The mystery of consciousness shows there may be a limit to what science alone can achieve

The progress of science in the last 400 years is mind-blowing. Who would have thought wed be able to trace the history of our universe to its origins 14 billion years ago? Science has increased the length and the quality...

Technology

Shiba Inu Faces Downtrend, XRP Undervalued, Ethereum Eyes Market Comeback

Amidst fluctuating crypto markets, Shiba Inu signals a potential downtrend, XRP appears undervalued, and Ethereum might be gearing up for a market resurgence, suggesting a mixed outlook for these major...

Senators Push for Stablecoin Regulation to Protect US Dollar Dominance

U.S. Senators Kirsten Gillibrand and Cynthia Lummis have introduced the Lummis-Gillibrand Payment Stablecoin Act. This legislation establishes stringent guidelines for stablecoin issuers to enhance consumer protection and...

Tesla's Flood Resilience Tested by Dubai's Historic Rainfall

As Dubai experienced its heaviest rainfall in 75 years, Tesla vehicles were spotted expertly maneuvering through the citys severely flooded streets. Social media footage shows these electric vehicles crossing water-logged...

Volkswagen Unveils New EV Platform in China to Cut Costs, Challenge BYD

In a strategic move to undercut rivals and boost market share, Volkswagen announced a new cost-effective EV platform in China, developed in partnership with XPeng, to launch in 2026. Volkswagen Partners with XPeng to...

Pepe Coin Climbs 6%: Market Braces for Potential Profit-Booking Selloff

Pepe Coin, the funny frog-themed meme cryptocurrency, has once again piqued the interest of crypto aficionados, with its price rising by an impressive 6% today. This revival coincides with a broader market recovery...