Scientists have obtained stem cells from pigs, sheep, and cattle without the need for serum, feeder cells, or antibiotics to pave the way for “manufacturing cell-cultured meat and breeding enhanced livestock”.
The researchers for the study were mainly from the University of Nottingham’s School of Biosciences in the UK, in collaboration with the Universities of Cambridge, Exeter, Tokyo, and Meijit.
According to the lead researcher, Ramiro Alberio, the ability to derive and maintain livestock stem cells under chemically defined conditions allows the development of novel food products, such as cultured meat.
He added that the newly-developed cell lines are a step-change from previous models for their unique ability to permanently grow to make muscle and fat.”
The stem cell lines can develop into multiple cell types, which can then be genetically manipulated through the Crispr/Cas9 gene-editing tool.
The results could broaden research into gene editing animals to improve productivity, adaptation to climate change, diet modifications, and the environmental impact of livestock production.
Alberio added the results allow gene editing to happen naturally over a long time selectively and rapidly to customize specific traits. This can accelerate the pace of genetic selection of livestock and cultured meat to improve productivity and the creation of healthier foods.
The research offers potential solutions that the food industry could use at scale amid a growing population to feed in a changing climate.
According to the study, the new chemically defined approach provides greater consistency and safety than the use of serum, making it an ideal solution for manufacturing new lab-grown food products.”.
It added that the use of serum has technical disadvantages, including its undefined nature, batch-to-batch variability in composition, and the risk of contamination.
The research, titled “Pluripotent stem cells related to embryonic disc exhibit common self-renewal requirements in diverse livestock species,” was published in the Development journal.
It was funded by BBSRC, EU (ERC), MRC and Wellcome Trust.


NASA Cuts Boeing Starliner Missions as SpaceX Pulls Ahead
Astronomers have discovered another puzzling interstellar object − this third one is big, bright and fast
Asian Stocks Waver as Trump Signals Fed Pick, Shutdown Deal and Tech Earnings Stir Markets
Panama Supreme Court Voids CK Hutchison Port Concessions, Raising Geopolitical and Trade Concerns
NASA Astronauts Wilmore and Williams Recover After Boeing Starliner Delay
Gold and Silver Prices Plunge as Trump Taps Kevin Warsh for Fed Chair
U.S. Eases Venezuela Oil Sanctions to Boost American Investment After Maduro Ouster
CDC Vaccine Review Sparks Controversy Over Thimerosal Study Citation
Trump Threatens Aircraft Tariffs as U.S.-Canada Jet Certification Dispute Escalates
Cogent Biosciences Soars 120% on Breakthrough Phase 3 Results for Bezuclastinib in GIST Treatment
Gold Prices Pull Back After Record Highs as January Rally Remains Strong
Elon Musk’s Empire: SpaceX, Tesla, and xAI Merger Talks Spark Investor Debate
Trump Signs Executive Order to Boost AI Research in Childhood Cancer
Gold Prices Stabilize in Asian Trade After Sharp Weekly Losses Amid Fed Uncertainty 



